Videos tagged 'School of Medicine'
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01:19
The effects of oral inorganic nitrate supplementation on lower limb perfusion and metabolism during exercise in patients with Peripheral Arterial Disease (PAD)
December 12, 2019
To determine mechanisms of ambulation improvements in PAD+IC following inorganic nitrate supplementation by performing graded plantar flexion exerc...
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01:05
Understanding infectious disease among home healthcare patients with a history of opioid use disorder
December 8, 2019
The study will help understand the prevalence and cost of infectious diseases among home healthcare patients with opioid use disorder history postd...
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01:23
The Impact of the Affordable Care Act’s dependent mandate on people living with HIV
December 8, 2019
This project will use econometrics methods to investigate the effects of the Affordable Care Act’s dependent mandate on HIV viral suppression for p...
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01:12
Quantitative MRI of body fat and risk of cardiometabolic diseases
December 8, 2019
Obesity and association with risk of cardiometabolic diseases including type 2 diabetes (T2D) and atherosclerosis. Weibin Shi School of Medicine ...
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01:20
Patients’, Family Caregivers’ and Clinicians’ Perspectives on ‘What Matters Most’ in the Management of End-stage Kidney Disease
December 8, 2019
A mixed-methods project to describe patient, family and clinicians’ perspectives on the most pressing palliative care needs in ESKD; This will info...
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01:33
Isolation and analysis of patient-derived malaria parasites
December 8, 2019
This project will generate new tools for the characterization of malaria parasites directly from the bloodstream of patients. Jennifer Lynn Güler ...
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01:22
Effects of perturbation of mRNA export pathways on neuron function
December 8, 2019
This project will explore the effect of CRISPR/Cas9 mediated mutations in the NXF1 gene on the outgrowth and function of primary hippocampal and co...
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01:15
Genetic Dissection of Vagal Motor Circuits Controlling Heart Function
December 8, 2019
Our project will define the synaptic circuitry and functional role of three novel neuron types in the nucleus ambiguous, the major parasympathetic ...
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01:11
Inducing Estrogen Receptors in ER-Negative Cancer Patients to Improve Outcomes
December 6, 2019
We will determine molecular pathways that allow expression of estrogen receptors (ER) in ER negative cells by performing a whole genome analysis on...
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01:29
Studying performance of polarized 3He gas in polymer pellets, a first step towards spin-polarized thermonuclear fusion
December 2, 2019
The energy output of a fusion reactor can be increased by using spin-polarized fuels. We will study performance of polarized 3He gas in pellets as ...
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01:32
Development of antibiotic resistance "in the wild"
December 2, 2019
The study of emergence of antibiotic resistance in real-life by modeling complex microbial communities, characterizing resistance in wastewater tre...
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01:30
Genetic modification of dietary effects on nutrient distribution and metabolism
December 1, 2019
The aim of the project is to investigate effects of different diets on nutrient distribution and metabolism in key metabolic tissues and evaluate h...
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01:22
Determination of Cardiac Reserve in Heart Failure using Pulse Wave Velocity Analysis
December 1, 2019
Heart failure is associated with diminished cardiac output, the amplitude of thearterial pulse wave velocity (PWV), and the magnitude of the reflec...
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01:24
The Impact of Weather and Climate on Hospital and Emergency Department Admissions in Virginia
November 25, 2019
In this project, we will examine the influence of long-term, seasonal, and daily weather and climate changes on hospital and emergency department a...
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01:14
Proof of Concept: Hit Alert Optics System
November 25, 2019
Injuries due to motor vehicle accidents have been reduced due to sensor technology. Inspired by this success story, sensor technology may be used t...
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01:42
Origami-inspired Expandable Soft Cages for Interbody Spinal Fusion
November 25, 2019
This research will explore the state-of-art design of origami-inspired, locally soft yet globally stiff, expandable biomedical cages for interbody ...
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01:28
Genetically-Encoded Norepinephrine Sensors
November 25, 2019
Norepinephrine (NE) ubiquitously mediates cell-to-cell communication, yet NE transmission remains poorly understood. We aim to develop NE sensors t...
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01:19
Development of a portable microfluidic system for field detection of Chemical Warfare Agents
November 25, 2019
Organophosphorus compounds (e.g., sarin) exhibit acute toxicity in humans as terrorist chemical warfare agents (CWA). We will develop a field-porta...
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01:33
Compassionate Schools Project Charlottesville
November 25, 2019
We will partner with Charlottesville City Schools to pilot a mindfulness-based health curriculum, develop and test a protocol to examine student he...
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01:32
Big data approaches for analyzing genomic intervals
November 25, 2019
Genomic interval data is frequently siloed, making it difficult to do cross-database analysis. In this project, we will develop data models and dis...
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01:06
An engineered probiotic for diabetic health
November 25, 2019
The team is utilizing a synthetic biology approach to engineer a probiotic that can convert dietary glucose to glycogen to minimize or control insu...
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01:11
Building an in vitro model for Neural Tube Defects
November 21, 2019
Establish an in vitro model to study formation and function of the nervous system in the pathological conditions of Neural Tube Defects. Christine...
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01:25
Comparing and Contrasting Artificial Neural Networks with Biological Neural Networks for Improved Representation Learning
November 21, 2019
We will study what are the implications of the different modes of operation of artificial neural networks and biological neural networks, and how d...
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01:20
Scalable Microfluidic Devices for Controlled Manufacturing of Micro-encapsulated Islets for Transplantation
November 20, 2019
Microfluidic approach to manufacturing controlled islet encapsulations for immunoprotection that can be scaled to produce large volumes of accurate...
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01:14
Using Design Thinking to Reshape Interprofessional Curricula for Healthcare Trainees
November 20, 2019
This project consists of Architecture, Nursing, and Medicine faculty, utilizing an Empathic Design Thinking Approach to Develop an Interprofessiona...
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01:22
Small molecule inhibitors of the CXXC domain, an epigenetic reader of DNA methylation
November 20, 2019
The CXXC domain functions as a reader of DNA methylation, binding to non-methylated CpGs. We will develop small molecule inhibitors and test effect...
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01:26
Brain Mechanisms of Pain Fear Acquisition and Extinction in Humans
November 19, 2019
Using intracranial recordings from patients with epilepsy, we aim to explore the brain mechanisms supporting pain-related fear acquisition and exti...
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01:21
Brain Synchrony During Student-Teacher Interactions
November 19, 2019
Real-world interactions involve multiple brains engaging together. Traditional neural metrics consider individuals in isolation. We will quantify e...
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01:14
Engineering Cell-adhesive Microparticle Systems to Enable in vitro Modeling of Mammalian Neural Development
November 19, 2019
Collaborative work in between the chemical engineering and cell biology departments will identify conditions to build an in vitro model to study no...
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01:33
Generation and characterization of a preclinical models to study DDX3X disorder
November 19, 2019
DDX3X mutation cause intellectual disabilities, seizures, autism, poor muscle tone, and slower physical developments. We propose to generate a fema...
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01:25
Long-term Effects on Astronaut Bone Health after Space Flight
November 19, 2019
This study will collect and analyze the relevant data from the LSAH in order to evaluate the long-term health risks associated with space flight. ...
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01:50
Neuromuscular pedicle for improved functional outcome of novel muscle regeneration scaffolds
November 19, 2019
We aim to generate clinical functional recovery after volumetric muscle loss by combining a neuromuscular pedicle embedded into novel scaffolds to ...
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01:31
Extracellular life style of an intracellular pathogen
November 12, 2019
We will test the hypothesis that before reaching the colon where it is an intracellular pathogen, S. flexneri develops an extracellular life style ...
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01:41
Development of Smart Algorithm for Cardiac Device Discrimination of Arrhythmias to Deliver Personalized Therapy
November 12, 2019
This project aims to develop an algorithm for defibrillators to recognize arrhythmias from upper and lower chambers of the heart to customize devic...
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01:14
Role of innate immunity in impaired neurodevelopment during zika virus infection
November 12, 2019
We will study neuroprogenitors by intraventricular injection of ZIKV into fetus of pregnant mice. We will assess the inflammatory signaling with hi...
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01:32
Predicting Functional Deficits after Volumetric Muscle Loss in the Lower Extremity
November 12, 2019
This project will evaluate patients with Volumetric Muscle loss as a result of injury using multiple methods with the goal of predicting functional...
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01:30
Nexus of Climate Change, Urban Infrastructure, Transportation and Health
November 4, 2019
Our goal is to establish the nexus among climate change, urban infrastructure, transportation and health using cross section study based on real ti...
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01:10
Visualizing glucose metabolism in live tissues to dissect metabolic regulation of immune function
November 4, 2019
A novel approach to analyze cellular metabolism outside the body, in complex living tissues. Rebecca R. Pompano College and Graduate School of Art...
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01:38
Modeling cerebral reperfusion injury using photoacoustic microscopy and oxygen-sensing nanoparticles
October 11, 2019
This project explores a novel non-invasive, dynamic imaging approach capable of quantifying functional changes in the brain following reperfusion a...